Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery

doi:10.4240/wjgs.120491

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 120491
Published online Aug 27, 2026. doi: 10.4240/wjgs.120491

Table 7 Comparison of clinical outcomes between two groups, n (%)/mean ± SD

Item	Control group (n = 49)	Intervention group (n = 49)	Statistic	P value
ICU LOS (days)	6.8 ± 2.4	5.2 ± 1.9	t = 3.643	< 0.001
MV duration (hours)	48.6 ± 18.4	36.2 ± 14.6	t = 3.668	< 0.001
28-day mortality	4 (8.2)	3 (6.1)	χ² = 0.154	0.695
Delirium incidence	12 (24.5)	4 (8.2)	χ² = 4.653	0.031
Respiratory depression	3 (6.1)	2 (4.1)	χ² = 0.211	0.646
Bradycardia	2 (4.1)	6 (12.2)	χ² = 1.965	0.161

ICU: Intensive care unit; LOS: Length of stay; MV: Mechanical ventilation.

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Citation: Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI: https://dx.doi.org/10.4240/wjgs.120491

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491 [DOI: 10.4240/wjgs.120491]

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