Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery

doi:10.4240/wjgs.120491

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World Journal of Gastrointestinal Surgery

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1948-9366

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 120491
Published online Aug 27, 2026. doi: 10.4240/wjgs.120491

Table 5 Comparison of organ function indicators between two groups, mean ± SD

Item	Control group (n = 49)	Intervention group (n = 49)	t value	P value
PaO₂/FiO₂ on admission (mmHg)	186.4 ± 42.8	182.6 ± 45.2	0.424	0.672
PaO₂/FiO₂ on POD 3 (mmHg)	218.6 ± 48.5	256.4 ± 52.8	3.676	< 0.001
PaO₂/FiO₂ on POD 5 (mmHg)	268.4 ± 54.2	312.6 ± 48.6	4.215	< 0.001
Creatinine on POD 3 (μmol/L)	128.6 ± 32.4	108.2 ± 28.6	3.281	0.001
Creatinine on POD 5 (μmol/L)	102.4 ± 26.8	86.5 ± 22.4	3.163	0.002
SOFA on POD 3	5.4 ± 1.8	4.2 ± 1.5	3.561	< 0.001
SOFA on POD 5	3.8 ± 1.4	2.6 ± 1.2	4.522	< 0.001

POD: Postoperative day; SOFA: Sequential Organ Failure Assessment.

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Citation: Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI: https://dx.doi.org/10.4240/wjgs.120491

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491 [DOI: 10.4240/wjgs.120491]

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