Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery

doi:10.4240/wjgs.120491

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 120491
Published online Aug 27, 2026. doi: 10.4240/wjgs.120491

Table 4 Comparison of sedation and pain assessment between two groups, mean ± SD

Item	Control group (n = 49)	Intervention group (n = 49)	Statistic	P value
Time to target sedation (hours)	3.8 ± 1.4	2.6 ± 1.1	t = 4.692	< 0.001
CPOT at 6 hours	2.4 ± 0.8	1.8 ± 0.6	t = 4.167	< 0.001
CPOT at 24 hours	1.9 ± 0.7	1.4 ± 0.5	t = 4.037	< 0.001
Total opioid (MEQ mg)	168.4 ± 42.6	124.8 ± 35.2	t = 5.486	< 0.001

CPOT: Critical Care Pain Observation Tool; MEQ: Morphine equivalent.

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Citation: Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI: https://dx.doi.org/10.4240/wjgs.120491

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491 [DOI: 10.4240/wjgs.120491]

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