Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery

doi:10.4240/wjgs.120491

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 120491
Published online Aug 27, 2026. doi: 10.4240/wjgs.120491

Table 3 Comparison of hemodynamic parameters between two groups, mean ± SD

Item	Control group (n = 49)	Intervention group (n = 49)	t value	P value
MAP at 12 hours (mmHg)	74.8 ± 9.2	78.6 ± 7.4	2.243	0.027
MAP at 24 hours (mmHg)	76.2 ± 8.4	80.8 ± 6.8	2.954	0.004
MAP at 48 hours (mmHg)	78.5 ± 7.6	82.4 ± 5.9	2.808	0.006
HR at 24 hours (bpm)	92.4 ± 12.6	86.2 ± 10.4	2.636	0.010
HR at 48 hours (bpm)	88.2 ± 10.8	82.6 ± 8.6	2.812	0.006

MAP: Mean arterial pressure; HR: Heart rate.

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Citation: Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI: https://dx.doi.org/10.4240/wjgs.120491

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491 [DOI: 10.4240/wjgs.120491]

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