Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery

doi:10.4240/wjgs.120491

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 120491
Published online Aug 27, 2026. doi: 10.4240/wjgs.120491

Table 2 Comparison of inflammatory markers between two groups, mean ± SD

Item	Control group (n = 49)	Intervention group (n = 49)	t value	P value
PCT on admission (ng/mL)	12.8 ± 5.6	13.2 ± 6.1	0.336	0.738
PCT on POD 3 (ng/mL)	6.4 ± 3.2	4.8 ± 2.5	2.746	0.007
PCT on POD 5 (ng/mL)	3.1 ± 1.8	1.9 ± 1.2	3.858	< 0.001
CRP on POD 3 (mg/L)	124.8 ± 36.2	98.6 ± 28.5	3.964	< 0.001
CRP on POD 5 (mg/L)	68.4 ± 22.6	48.2 ± 18.3	4.832	< 0.001
IL-6 on POD 3 (pg/mL)	168.5 ± 52.3	128.6 ± 42.8	4.112	< 0.001
IL-6 on POD 5 (pg/mL)	86.2 ± 28.4	62.5 ± 21.6	4.611	< 0.001

PCT: Procalcitonin; CRP: C-reactive protein; IL-6: Interleukin-6; POD: Postoperative day.

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Citation: Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI: https://dx.doi.org/10.4240/wjgs.120491

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491 [DOI: 10.4240/wjgs.120491]

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