Clinical effects of nutritional risk screening 2002-guided individualized nutritional intervention in postoperative colorectal cancer patients: A time-period comparison study

Table 4 Inflammatory response indicator comparison, mean ± SD

Indicator	Time point	Conventional group (n = 40)	ERAS group (n = 40)	Test statistic	P value
C-reactive protein (mg/L)
	Preoperative	4.2 ± 2.1	3.8 ± 1.9	t = 0.894	0.374
	Postop day 3	23.7 ± 9.1	15.2 ± 6.8	t = 4.652	< 0.001
	Postop day 7	14.8 ± 6.5	8.6 ± 4.2	t = 4.891	< 0.001
Interleukin-6 (pg/mL)
	Preoperative	3.2 ± 1.8	2.9 ± 1.6	t = 0.796	0.428
	Postop day 3	28.9 ± 11.2	18.4 ± 7.3	t = 4.721	< 0.001
	Postop day 7	19.7 ± 8.4	12.1 ± 5.8	t = 4.587	< 0.001
White blood cell count (× 109/L)
	Preoperative	6.8 ± 2.3	6.5 ± 2.1	t = 0.618	0.538
	Postop day 3	12.4 ± 3.7	9.8 ± 2.9	t = 3.423	< 0.01
	Postop day 7	9.6 ± 3.2	7.4 ± 2.5	t = 3.341	< 0.01
Neutrophil percentage (%)
	Preoperative	62.8 ± 8.4	61.5 ± 7.9	t = 0.721	0.473
	Postop day 3	78.9 ± 9.6	72.3 ± 8.2	t = 3.267	< 0.01
	Postop day 7	71.4 ± 8.8	66.2 ± 7.6	t = 2.816	< 0.01
Erythrocyte sedimentation rate (mm/hour)
	Preoperative	18.4 ± 12.6	16.8 ± 11.3	t = 0.594	0.554
	Postop day 7	42.8 ± 18.2	31.5 ± 14.7	t = 2.978	< 0.01
	Postop day 14	35.6 ± 15.9	24.8 ± 12.4	t = 3.321	< 0.01

ERAS: Enhanced recovery after surgery.