Efficacy of thrombin spray combined with clip closure after colorectal endoscopic mucosal resection and endoscopic submucosal dissection

Table 1 Comparison of general data between two groups, n (%)/mean ± SD

Item	Study group (n = 59)	Control group (n = 61)	Statistic	P value
Gender			χ2 = 0.417	0.519
Male	41 (69.5)	38 (62.3)
Female	18 (30.5)	23 (37.7)
Age (years)	56.8 ± 12.5	57.9 ± 13.2	t = 0.476	0.635
BMI (kg/m2)	23.8 ± 2.6	24.1 ± 2.4	t = 0.664	0.508
Lesion location			χ2 = 2.145	0.829
Rectum	18 (30.5)	21 (34.4)
Sigmoid colon	15 (25.4)	16 (26.2)
Descending colon	8 (13.6)	7 (11.5)
Transverse colon	10 (16.9)	9 (14.8)
Ascending colon	6 (10.2)	5 (8.2)
Cecum	2 (3.4)	3 (4.9)
Lesion size (cm)	2.0 ± 1.1	1.9 ± 1.0	t = 0.523	0.602
Surgical method			χ2 = 3.254	0.071
EMR	43 (72.9)	55 (90.2)
ESD	16 (27.1)	6 (9.8)
Comorbid underlying diseases
Hypertension	21 (35.6)	24 (39.3)	χ2 = 0.174	0.677
Diabetes	11 (18.6)	13 (21.3)	χ2 = 0.127	0.721
Coronary heart disease	5 (8.5)	7 (11.5)	χ2 = 0.285	0.593
Preoperative hemoglobin (g/L)	136.4 ± 15.3	138.1 ± 14.8	t = 0.624	0.534
Preoperative platelet count (× 109/L)	218.5 ± 52.3	223.6 ± 49.7	t = 0.551	0.583
Prothrombin time (second)	11.8 ± 1.2	11.6 ± 1.1	t = 0.959	0.339
Activated partial thromboplastin time (second)	28.3 ± 3.6	28.7 ± 3.4	t = 0.627	0.532

BMI: Body mass index; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection.