Impact of target volume delineation accuracy on locoregional control and survival after postoperative radiotherapy for colorectal cancer

doi:10.4240/wjgs.117559

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 117559
Published online Aug 27, 2026. doi: 10.4240/wjgs.117559

Table 7 Multivariate analysis of factors affecting overall survival

Factor	HR	95%CI	P value
Target delineation (inaccurate vs accurate)	2.398	1.334-4.311	0.004
pT stage (T4 vs T3)	1.586	0.872-2.885	0.132
pN stage (N2 vs N0-1)	1.946	1.132-3.345	0.016
Lymph node metastasis (N+ vs N0)	1.468	0.842-2.560	0.176
Vascular invasion (yes vs no)	1.324	0.736-2.382	0.348
Neural invasion (yes vs no)	1.512	0.846-2.702	0.162
Margin status (positive vs negative)	2.154	1.156-4.013	0.016
Preoperative CEA (elevated vs normal)	1.448	0.852-2.461	0.171

CEA: Carcinoembryonic antigen.

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Citation: Xing Y, Gu M. Impact of target volume delineation accuracy on locoregional control and survival after postoperative radiotherapy for colorectal cancer. World J Gastrointest Surg 2026; 18(8): 117559
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/117559.htm
DOI: https://dx.doi.org/10.4240/wjgs.117559