Clinical application of remimazolam benzenesulfonate in elderly patients undergoing laparoscopic cholecystectomy under intravenous general anesthesia

doi:10.4240/wjgs.v18.i7.121776

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World Journal of Gastrointestinal Surgery

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1948-9366

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jul 27, 2026; 18(7): 121776
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.121776

Table 5 Comparison of Visual Analogue Scale scores between 2 patient groups, mean ± SD

Parameters	Groups	Postoperative 1 hour	Postoperative 6 hours	Postoperative 24 hours
Postoperative pain management using PCIA (n = 81)	OG (n = 42)	2.55 ± 0.77	3.12 ± 0.55^a	4.79 ± 0.42^a^,^b
	CG (n = 39)	4.79 ± 0.41	4.49 ± 0.51	4.64 ± 0.49
	F_{group/time/interaction}	418.067/93.309/78.063
	P_{group/time/interaction}	< 0.001/< 0.001/< 0.001
Postoperative PCIA analgesia was not administered (n = 37)	OG (n = 17)	3.21 ± 0.70	4.29 ± 1.64^a	5.93 ± 1.49^a^,^b
	CG (n = 20)	5.55 ± 1.00	5.65 ± 1.46	6.30 ± 1.53
	F_{group/time/interaction}	20.999/15.934/5.697
	P_{group/time/interaction}	< 0.001/< 0.001/0.008

^aP < 0.05 within the group relative to 1 hour postoperatively.

^bP < 0.05 within the group relative to 6 hours postoperatively.

OG: Observation group; CG: Control group; PCIA: Patient-controlled intravenous analgesia.

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Citation: Wang QW, Wu L, Wang ZQ, Zhang J, Bai SC. Clinical application of remimazolam benzenesulfonate in elderly patients undergoing laparoscopic cholecystectomy under intravenous general anesthesia. World J Gastrointest Surg 2026; 18(7): 121776
URL: https://www.wjgnet.com/1948-9366/full/v18/i7/121776.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i7.121776

Wang QW, Wu L, Wang ZQ, Zhang J, Bai SC. Clinical application of remimazolam benzenesulfonate in elderly patients undergoing laparoscopic cholecystectomy under intravenous general anesthesia. World J Gastrointest Surg 2026; 18(7): 121776 [DOI: 10.4240/wjgs.v18.i7.121776]

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