Ziwu-Liuzhu-guided combined external therapy promotes wound healing in postoperative perianal fistulizing Crohn’s disease

Figure 4 Effects of different treatment strategies on overall postoperative efficacy in perianal fistulizing Crohn’s disease patients and evaluation of the efficacy prediction model. A: Composition of clinical efficacy outcomes across the three groups, including clinical cure, effective response, and ineffective response. The Ziwu-Liuzhu time-specific external treatment group had the highest proportion of clinical cure; B: Comparison of overall response rates among the three groups; The Ziwu-Liuzhu time-specific external treatment group showed the highest overall response rate; C: Forest plot of multivariable logistic regression analysis showing that the Ziwu-Liuzhu treatment strategy was significantly associated with treatment response and served as an independent predictor of favorable efficacy; D: Receiver operating characteristic curve of the efficacy prediction model constructed from the multivariable analysis. The curve was clearly above the diagonal reference line, indicating good discriminative performance of the model. OR: Odds ratio; CI: Confidence interval; AUC: Area under the curve; CRP: C-reactive protein; CDAI: Crohn’s Disease Activity Index; PDAI: Perianal Disease Activity Index; BMI: Body mass index.