Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients

Table 6 Comparison of the inflammatory markers between two groups, mean ± SD

Parameter	ESD group (n = 156)	ESTD group (n = 101)	t	P value
IL-8 (pg/mL)
Preoperative	15.32 ± 3.25	15.28 ± 3.43	0.090	0.929
Postoperative 3 days	20.58 ± 4.76	18.94 ± 4.12	2.844	0.005
Postoperative 7 days	15.89 ± 3.82	14.76 ± 3.05	2.629	0.009
TNF-α (pg/mL)
Preoperative	8.45 ± 1.58	8.41 ± 1.62	0.205	0.838
Postoperative 3 days	11.02 ± 2.34	10.15 ± 2.01	3.081	0.002
Postoperative 7 days	8.76 ± 1.95	8.12 ± 1.74	2.691	0.008
hs-CRP (mg/L)
Preoperative	3.44 ± 1.02	3.39 ± 1.08	0.372	0.710
Postoperative 3 days	10.38 ± 3.16	9.31 ± 2.85	2.744	0.006
Postoperative 7 days	6.05 ± 1.83	5.42 ± 1.76	2.726	0.007

ESD: Endoscopic submucosal dissection; ESTD: Endoscopic submucosal tunnel dissection; IL-8: Interleukin-8; TNF-α: Tumor necrosis factor-alpha; hs-CRP: High-sensitivity C-reactive protein.