Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients

doi:10.4240/wjgs.v18.i7.120740

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jul 27, 2026; 18(7): 120740
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.120740

Table 2 Comparison of disease characteristics between two groups, n (%)/mean ± SD

Parameter	ESD group (n = 156)	ESTD group (n = 101)	t/χ²	P value
Histological type			0.345	0.557
ESCC	109 (69.87)	74 (73.27)
BE-EAC	47 (30.13)	27 (26.73)
TNM staging			0.086	0.769
Tis	62 (39.74)	42 (41.58)
T1a	94 (60.26)	59 (58.42)
Tumor invasion depth			0.441	0.802
M1	53 (33.97)	37 (36.63)
M2	62 (39.74)	36 (35.64)
M3	41 (26.28)	28 (27.72)
Maximum tumor diameter (mm)	33.86 ± 10.98	31.92 ± 9.75	1.440	0.151
Tumor location			1.756	0.416
Upper esophagus	16 (10.26)	6 (5.94)
Middle esophagus	58 (37.18)	36 (35.64)
Lower esophagus	82 (52.56)	59 (58.42)
Macroscopic type			0.637	0.888
Elevated type	40 (25.64)	29 (28.71)
Flat type	88 (56.41)	52 (51.49)
Depressed type	23 (14.74)	16 (15.84)
Mixed types	5 (3.21)	4 (3.96)
Circumferential extent			1.139	0.286
< 50%	98 (62.82)	70 (69.31)
50%-75%	58 (37.18)	31 (30.69)

ESD: Endoscopic submucosal dissection; ESTD: Endoscopic submucosal tunnel dissection; ESCC: Esophageal squamous cell carcinoma; BE-EAC: Barrett’s esophagus-associated adenocarcinoma; TNM: Tumor, node, and metastasis.

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Citation: Zhang D, Hao XX, Zhang C, Liang Y. Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients. World J Gastrointest Surg 2026; 18(7): 120740
URL: https://www.wjgnet.com/1948-9366/full/v18/i7/120740.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i7.120740

Zhang D, Hao XX, Zhang C, Liang Y. Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients. World J Gastrointest Surg 2026; 18(7): 120740 [DOI: 10.4240/wjgs.v18.i7.120740]

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