Albumin as a predictor in a nomogram for severe complications following gastrointestinal surgery and how to manage it

Table 3 Stratified multivariable logistic regression analysis of lowest postoperative albumin levels within 5 days on severe complications

Characteristics	Univariable logistic regression		Multivariable logistic regression
	OR (95%CI)	P value	OR (95%CI)	P value
Age (years)	1.003 (1.014-1.053)	0.001	1.022 (1.000-1.043)	0.047
Sex
Male	Reference		-
Female	1.074 (0.718-1.607)	0.729	-
American Society of Anesthesiologists grade
Low	Reference		Reference
High	2.608 (1.669-4.075)	< 0.001	2.085 (1.253-3.467)	0.005
Operation
Laparoscopy	Reference		Reference
Laparotomy	1.695 (1.141-2.519)	0.009	1.203 (0.775-1.886)	0.410
Surgical duration (minutes)	1.005 (1.003-1.007)	< 0.001	1.004 (1.002-1.007)	< 0.001
Preoperative total bilirubin (μmol/L)	1.012 (0.987-1.038)	0.341	-
Preoperative alanine aminotransferase (U/L)	1.001 (0.990-1.012)	0.893	-
Preoperative aspartate aminotransferase (U/L)	1.012 (0.995-1.029)	0.182	-
Preoperative gamma-glutamyl transferase (U/L)	1.002 (0.998-1.005)	0.355	-
Lowest postoperative albumin within 5 days (g/L)
(25, 30)	3.066 (1.666-5.644)	< 0.001	2.331 (1.214-4.476)	0.011
(30, 35)	2.256 (1.328-3.832)	0.003	1.725 (0.978-3.043)	0.060
(35, 40)	Reference		Reference

OR: Odds ratio.