Effect of propofol and remimazolam on post-induction hypotension in hypertensive patients undergoing laparoscopic cholecystectomy

doi:10.4240/wjgs.120158

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World Journal of Gastrointestinal Surgery

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1948-9366

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 120158
Published online Jun 27, 2026. doi: 10.4240/wjgs.120158

Table 1 Comparison of general data between the two groups of patients, n (%)/mean ± SD

Variable	Remimazolam group (n = 88)	Propofol group (n = 89)	t/χ² value	P value
Male	46 (52.27)	45 (50.56)	0.051	0.882
Age (year)	65.92 ± 8.15	66.45 ± 7.89	0.418	0.677
BMI (kg/m²)	24.58 ± 3.02	24.92 ± 2.95	0.736	0.462
ASA classification (II/III)	64/24	66/23	0.156	0.925
Diabetes	22(25.00)	25(28.09)	0.321	0.572
Type of antihypertensive drugs
ACEI/ARB	65 (73.86)	74 (83.15)	0.233	0.233
CCB	32 (36.36)	42 (47.19)	0.173	0.173
Diuretic	20 (22.73)	18 (20.22)	0.666	0.666
Others	2 (2.27)	3 (3.37)	0.667	0.667
Duration of hypertension (year)	8.65 ± 3.22	8.98 ± 3.45	0.762	0.447
Preoperative systolic pressure (mmHg)	139.65 ± 10.32	139.91 ± 9.87	0.385	0.700
Preoperative diastolic pressure (mmHg)	88.36 ± 6.21	87.92 ± 5.98	0.452	0.652
Surgical duration (minute)	58.12 ± 11.65	58.89 ± 12.03	0.436	0.663
Intraoperative blood loss (mL)	14.89 ± 8.35	15.76 ± 8.12	0.568	0.570

BMI: Body mass index; ASA: American Society of Anesthesiologists; ACEI: Angiotensin-converting enzyme inhibitor; ARB: Angiotensin receptor blocker; CCB: Calcium channel blocker.

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Citation: Zhang YT, Bai SC. Effect of propofol and remimazolam on post-induction hypotension in hypertensive patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(6): 120158
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/120158.htm
DOI: https://dx.doi.org/10.4240/wjgs.120158

Zhang YT, Bai SC. Effect of propofol and remimazolam on post-induction hypotension in hypertensive patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(6): 120158 [DOI: 10.4240/wjgs.120158]

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