Anti-reflux mucosectomy is associated with better short-term symptoms than double-dose proton pump inhibitor in reflux esophagitis patients

doi:10.4240/wjgs.119941

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 119941
Published online Jun 27, 2026. doi: 10.4240/wjgs.119941

Table 2 Patient reported preoperative symptom between the two groups, n (%)

Characteristic	ARMS (n = 14)	Double-dose PPI (n = 14)	P value
Preop symptoms
Belching	5 (35.7)	6 (42.9)	0.699
Reflux	12 (85.7)	11 (78.6)	0.622
Heartburn	9 (64.3)	10 (71.4)	0.686
Regurgitation	8 (57.1)	8 (57.1)	1.000
Dysphagia	4 (28.6)	3 (21.4)	0.663
Cough	2 (14.3)	3 (21.4)	0.622
Laryngitis	8 (57.1)	7 (50.0)	0.705
Dyspnea	1 (7.1)	2 (14.3)	0.541
Epigastric/chest pain	7 (50.0)	6 (42.9)	0.705
Water brash	6 (42.9)	5 (35.7)	0.699
Globus sensation	7 (50.0)	8 (57.1)	0.705
Nausea	2 (14.3)	3 (21.4)	0.622
Emesis	1 (7.1)	1 (7.1)	1.000
Nocturnal symptoms	9 (64.3)	10 (71.4)	0.686

PPI: Proton pump inhibitor; ARMS: Anti-reflux mucosectomy.

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Citation: Jiang WJ, Liu J, Liu YL, Tang MD, Sheng Y, Wang YT. Anti-reflux mucosectomy is associated with better short-term symptoms than double-dose proton pump inhibitor in reflux esophagitis patients. World J Gastrointest Surg 2026; 18(6): 119941
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/119941.htm
DOI: https://dx.doi.org/10.4240/wjgs.119941

Jiang WJ, Liu J, Liu YL, Tang MD, Sheng Y, Wang YT. Anti-reflux mucosectomy is associated with better short-term symptoms than double-dose proton pump inhibitor in reflux esophagitis patients. World J Gastrointest Surg 2026; 18(6): 119941 [DOI: 10.4240/wjgs.119941]

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