Efficacy of linaclotide with polyethylene glycol at high risk of inadequate bowel preparation: A randomized controlled trial

doi:10.4240/wjgs.119538

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 119538
Published online Jun 27, 2026. doi: 10.4240/wjgs.119538

Table 4 Comparison of polyp characters in patients with detected polyps between the two groups, mean ± SD

Groups	3 L PEG (n = 50)	Linaclotide + 3 L PEG (n = 53)	Difference between groups (95%CI)	P value
Number of polyps	2.580 ± 1.808	2.528 ± 1.772	-0.052 (-0.752 to 0.648)	0.829
Size of polyps	1.034 ± 0.920	1.066 ± 0.864	0.032 (-0.317 to 0.381)	0.723
Number of adenoma	1.620 ± 1.872	1.528 ± 1.612	-0.092 (-0.774 to 0.590)	0.988

CI: Confidence interval; PEG: Polyethylene glycol.

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Citation: Li WM, Wang XP, Li YX, Wang YD, Sun YJ, Li GD, Wu JQ. Efficacy of linaclotide with polyethylene glycol at high risk of inadequate bowel preparation: A randomized controlled trial. World J Gastrointest Surg 2026; 18(6): 119538
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/119538.htm
DOI: https://dx.doi.org/10.4240/wjgs.119538

Li WM, Wang XP, Li YX, Wang YD, Sun YJ, Li GD, Wu JQ. Efficacy of linaclotide with polyethylene glycol at high risk of inadequate bowel preparation: A randomized controlled trial. World J Gastrointest Surg 2026; 18(6): 119538 [DOI: 10.4240/wjgs.119538]

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