Effects of esketamine on perioperative renal injury in paediatric patients undergoing living donor liver transplantation

doi:10.4240/wjgs.119494

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World Journal of Gastrointestinal Surgery

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1948-9366

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 119494
Published online Jun 27, 2026. doi: 10.4240/wjgs.119494

Table 2 Comparison of serum creatinine levels and acute kidney injury incidence between groups

Time	Group E Scr (μmol/L)	Group C Scr (μmol/L)	P value	Cohen's d
T1	18.84 ± 6.11	20.78 ± 5.67	0.207	-0.329
T2	22.26 ± 7.05	22.59 ± 6.85	0.855	-0.047
T3	40.56 ± 15.4^a^,^b	60.37 ± 15.4^b	< 0.05	-1.286
T4	36.35 ± 8.96^a^,^b	58.93 ± 12.57^b	< 0.05	-2.069
T5	34.64 ± 5.66^a^,^b	53.51 ± 8.69^b	< 0.05	-2.573
AKI	11 (36.7)	15 (50.0)	0.435	-

^aP < 0.05 vs group C.

^bP < 0.05 vs T1.

Data were showed as n (%) or mean ± SD. T1: 5 minutes after anaesthetic induction; T2: 30 minutes during the anhepatic phase; T3: 3 hours during the new liver phase; T4: 24 hours postoperatively; T5: 72 hours postoperatively. Scr: Serum creatinine; AKI: Acute kidney injury.

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Citation: Li HX, Cao GZ, Weng YQ, Dong AL, Gao W, Zhu M, Che L, Yu WL. Effects of esketamine on perioperative renal injury in paediatric patients undergoing living donor liver transplantation. World J Gastrointest Surg 2026; 18(6): 119494
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/119494.htm
DOI: https://dx.doi.org/10.4240/wjgs.119494

Li HX, Cao GZ, Weng YQ, Dong AL, Gao W, Zhu M, Che L, Yu WL. Effects of esketamine on perioperative renal injury in paediatric patients undergoing living donor liver transplantation. World J Gastrointest Surg 2026; 18(6): 119494 [DOI: 10.4240/wjgs.119494]

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