Comprehensive strategy for preventing unplanned extubation in patients with post-operative delirium after gastrointestinal surgery

Table 6 Multivariate Cox regression analysis of unplanned extubation risk (n = 118)

Predictor	Comparison	HR	95%CI	P value
Mean daily fluctuation in RASS score	> 1.5 vs ≤ 1.5	3.850	1.421-10.447	0.008
Frequency of extubation intention behaviors	≥ 3 times/24 hours vs < 3 times/24 hours	4.210	1.561-11.366	0.005
Reduction in the IL-6 level on post-op day 3	< 30% vs ≥ 30%	2.930	1.101-7.818	0.031
Intervention response time	> 60 seconds vs ≤ 60 seconds	3.120	1.181-8.238	0.022
Restraint usage rate	High (> 50% of ICU days) vs low	2.780	1.051-7.358	0.039
Nursing assessment completion rate	Low (< 90%) vs high (≥ 90%)	3.050	1.142-8.147	0.026

RASS: Richmond Agitation-Sedation Scale; IL: Interleukin; post-op: Post-operative; ICU: Intensive care unit; HR: Hazard ratio; CI: Confidence interval.