Expression of LHFPL2 in hepatocellular carcinoma and its association with prognosis after transarterial chemoembolization

doi:10.4240/wjgs.116682

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jun 27, 2026; 18(6): 116682
Published online Jun 27, 2026. doi: 10.4240/wjgs.116682

Table 3 Univariate and multivariate Cox analyses of prognostic survival in patients with hepatocellular carcinoma

Index	Univariate analysis			Multiple factor
Index	HR	95%CI	P value	HR	95%CI	P value
Age	1.040	1.000-1.084	0.067	-	-	-
Sex	0.688	0.318-2.920	0.342	-	-	-
HBV carrier	1.931	0.877-4.253	0.102	-	-	-
Cirrhosis	1.977	0.925-4.226	0.079	-	-	-
AFP ≥ 400 ng/mL	13.483	4.634-39.226	< 0.001	38.632	5.274-282.970	< 0.001
Tumor size > 3 cm	1.695	0.758-3.787	0.198	-	-	-
Poor differentiation	0.584	0.341-1.001	0.050	-	-	-
High LHFPL2	4.490	1.950-10.341	< 0.001	5.408	1.569-18.642	0.008
TACE refractoriness	12.444	4.131-37.489	< 0.001	6.955	1.458-33.170	0.015

CI: Confidence interval; HR: Hazard ratio; HBV: Hepatitis B virus; AFP: Alpha-fetoprotein; HFPL2: Lipoma HMGIC fusion partner-like 2; TACE: Transarterial chemoembolization.

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Citation: Sun L, Chen K, Zhu XL. Expression of LHFPL2 in hepatocellular carcinoma and its association with prognosis after transarterial chemoembolization. World J Gastrointest Surg 2026; 18(6): 116682
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/116682.htm
DOI: https://dx.doi.org/10.4240/wjgs.116682

Sun L, Chen K, Zhu XL. Expression of LHFPL2 in hepatocellular carcinoma and its association with prognosis after transarterial chemoembolization. World J Gastrointest Surg 2026; 18(6): 116682 [DOI: 10.4240/wjgs.116682]

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