Spleen stiffness accurately tracks early and sustained portal pressure changes after transjugular intrahepatic portosystemic shunt

doi:10.4240/wjgs.v18.i5.118030

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World Journal of Gastrointestinal Surgery

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1948-9366

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World J Gastrointest Surg. May 27, 2026; 18(5): 118030
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.118030

Table 2 Changes in laboratory parameters before and after transjugular intrahepatic portosystemic shunt placement

Characteristics	Before TIPS (n = 39)	After TIPS (n = 39)	P value
ALT (U/L)	33.97 ± 34.05	67.79 ± 79.35	< 0.001
AST (U/L)	45.41 ± 55.65	97.77 ± 117.26	< 0.001
ALP (U/L)	113.13 ± 130.62	119.23 ± 202.33	0.261
γ-GT (U/L)	78.18 ± 116.36	73.10 ± 107.24	0.085
Serum albumin (g/L)	34.04 ± 5.10	33.08 ± 5.61	0.207
Serum total bilirubin (μmol/L)	26.31 ± 15.94	33.72 ± 21.84	0.005
Serum creatinine (μmol/L)	74.48 ± 30.78	75.03 ± 32.77	0.867
Platelets (10⁹/L)	90.28 ± 68.96	33.97 ± 34.05	0.460
INR	1.27 ± 0.15	1.38 ± 0.24	< 0.001
PT	15.22 ± 1.60	16.93 ± 2.27	< 0.001
WBC (10⁹/L)	4.44 ± 3.54	6.34 ± 4.25	0.001
Hemoglobin (g/L)	87.72 ± 26.66	86.18 ± 29.12	0.464

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; γ-GT: Γ-glutamyl transferase; INR: International normalised ratio; PT: Prothrombin time; WBC: White blood cells; TIPS: Transjugular intrahepatic portosystemic shunt.

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Citation: Zhou RQ, Yang PJ, Liu LG, Zhang JB, Ye ZD, Tan HD. Spleen stiffness accurately tracks early and sustained portal pressure changes after transjugular intrahepatic portosystemic shunt. World J Gastrointest Surg 2026; 18(5): 118030
URL: https://www.wjgnet.com/1948-9366/full/v18/i5/118030.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i5.118030

Zhou RQ, Yang PJ, Liu LG, Zhang JB, Ye ZD, Tan HD. Spleen stiffness accurately tracks early and sustained portal pressure changes after transjugular intrahepatic portosystemic shunt. World J Gastrointest Surg 2026; 18(5): 118030 [DOI: 10.4240/wjgs.v18.i5.118030]

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