Dynamic monitoring of serum tumor markers in predicting recurrence after radical gastrectomy for gastric cancer

Table 1 Comparison of clinical pathological characteristics between recurrence and non-recurrence groups, n (%)

Characteristic	Recurrence group (n = 68)	Non-recurrence group (n = 145)	Test statistic	P value
Age (years)	61.8 ± 10.2	60.5 ± 11.4	t = 0.816	0.416
Gender			χ² = 0.125	0.724
Male	46 (67.6)	95 (65.5)
Female	22 (32.4)	50 (34.5)
BMI (kg/m²)	22.8 ± 3.1	23.2 ± 2.9	t = 0.925	0.356
Underlying diseases	28 (41.2)	53 (36.6)	χ² = 0.486	0.486
Tumor location			χ² = 2.815	0.245
Upper stomach	15 (22.1)	25 (17.2)
Body of stomach	23 (33.8)	48 (33.1)
Lower stomach	30 (44.1)	72 (49.7)
Histological type			χ² = 1.847	0.397
Papillary adenocarcinoma	8 (11.8)	22 (15.2)
Tubular adenocarcinoma	35 (51.5)	81 (55.9)
Mucinous adenocarcinoma	15 (22.1)	26 (17.9)
Signet ring cell carcinoma	10 (14.7)	16 (11.0)
Tumor size			χ² = 8.927	0.003
< 5 cm	28 (41.2)	88 (60.7)
≥ 5 cm	40 (58.8)	57 (39.3)
Degree of differentiation			χ² = 11.456	< 0.001
Well-moderately differentiated	18 (26.5)	71 (49.0)
Poorly differentiated-undifferentiated	50 (73.5)	74 (51.0)
T stage			χ² = 18.245	< 0.001
T1-T2	12 (17.6)	62 (42.8)
T3-T4	56 (82.4)	83 (57.2)
N stage			χ² = 24.186	< 0.001
N0	8 (11.8)	52 (35.9)
N1-N3	60 (88.2)	93 (64.1)
TNM stage			χ² = 21.347	< 0.001
Stage I	5 (7.4)	38 (26.2)
Stage II	22 (32.4)	58 (40.0)
Stage III	41 (60.3)	49 (33.8)
Vascular invasion	42 (61.8)	55 (37.9)	χ² = 11.258	< 0.001
Neural invasion	38 (55.9)	48 (33.1)	χ² = 10.525	0.001
Surgical method			χ² = 0.846	0.358
Distal subtotal gastrectomy	46 (67.6)	107 (73.8)
Total gastrectomy	22 (32.4)	38 (26.2)
Extent of lymph node dissection			χ² = 1.124	0.289
D1+	15 (22.1)	42 (29.0)
D2	53 (77.9)	103 (71.0)

TNM: Tumor-node-metastasis; BMI: Body mass index.