Visceral obesity exacerbates perioperative muscle loss and impairs survival in colorectal cancer

doi:10.4240/wjgs.v18.i5.116822

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World Journal of Gastrointestinal Surgery

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1948-9366

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. May 27, 2026; 18(5): 116822
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.116822

Table 3 Factors associated with skeletal muscle loss

	SML
	Single factor OR (95%CI)	P value	Multivariate OR (95%CI)	P value
Age
≤ 65	Reference
> 65	1.144 (0.742-1.766)	0.542
Gender
Female	Reference
Male	0.945 (0.608-1.469)	0.801
BMI	1.017 (0.95-1.089)	0.622	0.846 (0.757-0.946)	0.003
VFA
Low VFA	Reference
High VFA	2.110 (1.34-3.322)	0.001	2.557 (1.518-4.305)	0.000
Preoperative SMI	1.035 (1.007-1.064)	0.016	1.082(1.035-1.131)	0.000
Prophylactic ileostomy condition
No	Reference
Yes	1.733 (1.004-2.99)	0.048	1.936 (1.086-3.449)	0.025

BMI: Body mass index; VFA: Visceral fat area; SMI: Skeletal muscle index; SML: Skeletal muscle loss; OR: Odds ratio; CI: Confidence interval.

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Citation: Wang Y, Bu J, Zhan CY, Xu DL, Hu JQ, Zhang MH, Zhu KJ, Qi Y. Visceral obesity exacerbates perioperative muscle loss and impairs survival in colorectal cancer. World J Gastrointest Surg 2026; 18(5): 116822
URL: https://www.wjgnet.com/1948-9366/full/v18/i5/116822.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i5.116822

Wang Y, Bu J, Zhan CY, Xu DL, Hu JQ, Zhang MH, Zhu KJ, Qi Y. Visceral obesity exacerbates perioperative muscle loss and impairs survival in colorectal cancer. World J Gastrointest Surg 2026; 18(5): 116822 [DOI: 10.4240/wjgs.v18.i5.116822]

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