Correlation of systemic immune-inflammation and prognostic nutritional indices with pathological characteristics and prognosis in gastric cancer

Table 2 Correlation of Prognostic Nutritional Index and clinical pathological characteristics of gastric cancer patients, median (interquartile rage)/mean ± SD

Indicator	PNI level	Z/t	P value
Gender		-0.102	0.919
Male (n = 70)	44.00 (40.00-50.00)
Female (n = 37)	43.00 (40.50-49.50)
Age (years)		-0.323	0.746
< 60 (n = 63)	44.00 (40.00-49.00)
≥ 60 (n = 44)	44.00 (39.00-50.00)
Maximum tumor diameter (cm)		0.875	0.383
< 4 (n = 54)	45.98 ± 9.16
≥ 4 (n = 53)	44.47 ± 8.67
Differentiation degree		2.890	0.005
Moderate-to-high differentiation (n = 35)	48.69 ± 9.20
Low differentiation (n = 72)	43.56 ± 8.32
Tumor location		0.742	0.479
Cardia and fundic region (n = 19)	46.74 ± 9.09
Gastric body (n = 22)	46.41 ± 9.37
Pyloric region (n = 66)	44.41 ± 8.74
Borrmann type		-0.845	0.398
I-II (n = 35)	44.00 (39.00-49.00)
III-IV (n = 72)	44.00 (41.00-50.00)
Invasion depth		-3.775	< 0.001
T1-T2 (n = 27)	50.00 (44.00-57.00)
T3-T4 (n = 80)	43.00 (39.00-48.00)
Metastases to lymph nodes		1.134	0.260
N0-N1 (n = 54)	46.20 ± 8.64
N2-N3 (n = 53)	44.25 ± 9.15
Distant metastasis		2.255	0.026
M0 (n = 68)	46.68 ± 10.01
M1 (n = 39)	42.72 ± 5.88
TNM staging		-4.020	< 0.001
I-II (n = 51)	48.00 (43.00-55.00)
III-IV (n = 56)	41.00 (38.25-45.00)
CA199 (U/mL)		-2.059	0.040
< 35 (n = 81)	46.00 (39.50-52.00)
≥ 35 (n = 26)	43.00 (40.00-44.25)
CEA (ng/mL)		1.506	0.135
< 5 (n = 86)	48.67 ± 8.02
≥ 5 (n = 21)	45.71 ± 8.30

TNM: Tumor-node-metastasis; CA199: Carbohydrate antigen 199; CEA: Carcinoembryonic antigen; PNI: Prognostic Nutritional Index.