Correlation of systemic immune-inflammation and prognostic nutritional indices with pathological characteristics and prognosis in gastric cancer

Table 1 Correlation between Systemic Immune-Inflammation and clinical pathological characteristics of gastric cancer patients, mean ± SD

Indicator	SII level	t/F	P value
Gender		1.845	0.068
Male (n = 70)	617.77 ± 176.42
Female (n = 37)	545.41 ± 221.25
Age (years)		0.210	0.834
< 60 (n = 63)	589.43 ± 200.39
≥ 60 (n = 44)	597.50 ± 189.57
Maximum tumor diameter (cm)		2.040	0.044
< 4 (n = 54)	555.17 ± 197.23
≥ 4 (n = 53)	631.04 ± 187.14
Differentiation degree		1.612	0.110
Moderate-to-high differentiation (n = 35)	549.46 ± 171.24
Low differentiation (n = 72)	613.79 ± 203.57
Tumor location		0.988	0.376
Cardia and fundic region (n = 19)	542.05 ± 211.04
Gastric body (n = 22)	580.41 ± 177.48
Pyloric region (n = 66)	611.45 ± 196.05
Borrmann type		0.241	0.810
I-II (n = 35)	605.09 ± 204.47
III-IV (n = 72)	613.45 ± 147.42
Invasion depth		2.834	0.006
T1-T2 (n = 27)	503.63 ± 199.78
T3-T4 (n = 80)	622.83 ± 185.28
Metastases to lymph nodes		3.681	< 0.001
N0-N1 (n = 54)	527.69 ± 212.26
N2-N3 (n = 53)	659.04 ± 151.11
Distant metastasis		4.211	< 0.001
M0 (n = 68)	536.84 ± 192.37
M1 (n = 39)	690.23 ± 160.1
TNM staging		2.653	0.009
I-II (n = 51)	539.90 ± 189.84
III-IV (n = 56)	640.88 ± 188.90
CA199 (U/mL)		3.336	0.001
< 35 (n = 81)	558.68 ± 186.57
≥ 35 (n = 26)	698.88 ± 186.03
CEA (ng/mL)		0.195	0.846
< 5 (n = 86)	590.92 ± 197.96
≥ 5 (n = 21)	600.24 ± 187.65

TNM: Tumor-node-metastasis; CA199: Carbohydrate antigen 199; CEA: Carcinoembryonic antigen; SII: Systemic Immune-Inflammation Index.