Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery

Table 4 Relationship between delirium and inflammatory factor levels

Time	Characteristic	Delirium	Non-delirium	P value
n		37	136
Pre	IL-1β	1.11 (0.75, 1.54)	1.15 (0.78, 1.56)	< 0.753
	IL-2	1.91 (1.35, 2.21)	1.95 (1.38, 2.25)	< 0.657
	IL-6	8.8 (7.7, 10.1)	8.6 (7.6, 10.3)	0.843
	IL-8	24 (19, 28)	20 (12, 48)	0.579
	IL-10	1.11 (0.88, 1.44)	1.18 (0.90, 1.46)	0.765
	TNF-α	1.69 (1.03, 2.54)	1.72 (1.05, 2.50)	0.821
Day 1	IL-1β	1.84 (1.44, 2.89)	1.68 (0.99, 3.88)	0.259
	IL-2	1.76 (1.57, 1.95)	2.39 (1.69, 4.07)	< 0.001
	IL-6	64 (42, 85)	38 (22, 83)	< 0.001
	IL-8	26 (20, 35)	15 (9, 26)	< 0.001
	IL-10	3.2 (2.1, 3.8)	6.0 (3.1, 8.8)	< 0.001
	TNF-α	1.79 (1.22, 2.67)	1.94 (1.39, 2.72)	0.461
Day 2	IL-1β	2.21 (1.78, 2.71)	2.06 (1.44, 3.89)	0.789
	IL-2	1.36 (1.11, 1.84)	2.48 (1.63, 3.83)	< 0.001
	IL-6	66 (37, 87)	63 (28, 107)	0.770
	IL-8	40 (31, 46)	28 (16, 54)	0.019
	IL-10	2.4 (1.7, 3.7)	5.8 (4.2, 9.3)	< 0.001
	TNF-α	2.00 (1.21, 2.84)	2.42 (1.76, 3.44)	0.021
Day 7	IL-1β	1.93 (1.13, 3.58)	1.24 (0.93, 1.55)	< 0.001
	IL-2	1.55 (1.30, 1.80)	2.34 (1.67, 4.22)	< 0.001
	IL-6	22 (11, 39)	17 (9, 32)	0.038
	IL-8	18 (14, 22)	22 (11, 62)	0.165
	IL-10	1.89 (1.45, 2.50)	4.18 (3.17, 6.58)	< 0.001
	TNF-α	2.30 (1.76, 3.21)	1.99 (1.35, 2.53)	0.003

TNF-α: Tumor necrosis factor-α; IL: Interleukin.