Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery

doi:10.4240/wjgs.v18.i4.119293

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Apr 27, 2026; 18(4): 119293
Published online Apr 27, 2026. doi: 10.4240/wjgs.v18.i4.119293

Table 1 Baseline characteristics of study subjects, n (%)

Characteristic	Control group	Oxiracetam group	Statistic	P value
n	91	82
Age (years old)	71 ± 9	71 ± 9	t = 0.09	0.926¹
Gender			χ² = 0.31	0.576²
Female	38 (41.8)	33 (40.2)
Male	53 (58.2)	49 (59.8)
BMI, mean ± SD	23.1 ± 4.1	23.3 ± 3.9	t = -0.46	0.645¹
ASA grade			χ² = 1.66	0.198²
II	72 (79.1)	65 (79.3)
III	19 (20.9)	17 (20.7)
Diagnosis			χ² = 3.68	0.165²
Colorectal cancer	63 (69.2)	57(69.5)
Others	28 (30.8)	25 (30.5)
Operation time (minute)	246 ± 132	246 ± 127	t = -0.05	0.962¹
Intraoperative blood loss (mL)	103 ± 134	113 ± 242	t = -0.34	0.736¹
Intraoperative blood transfusion	11 (12.1)	9 (11.0)	χ² = 0.20	0.654²
Hospital stay (days)	22.5 ± 5.0	20.7 ± 7.9	t = 1.83	0.070¹

¹Welch two sample t-test.

²Pearson’s χ² test.

ASA: American Society of Anesthesiologists; BMI: Body mass index.

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Citation: Lv BS, Wang W, Jin M, Ma Y, Wang JL, Gao H. Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery. World J Gastrointest Surg 2026; 18(4): 119293
URL: https://www.wjgnet.com/1948-9366/full/v18/i4/119293.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i4.119293

Lv BS, Wang W, Jin M, Ma Y, Wang JL, Gao H. Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery. World J Gastrointest Surg 2026; 18(4): 119293 [DOI: 10.4240/wjgs.v18.i4.119293]

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