Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China

doi:10.4240/wjgs.v18.i4.117397

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Apr 27, 2026; 18(4): 117397
Published online Apr 27, 2026. doi: 10.4240/wjgs.v18.i4.117397

Table 5 The association between Helicobacter pylori infection levels and the proportion of different types of colorectal polyps and colorectal cancer, n (%)

	*H. pylori +*	*H. pylori ++*	*H. pylori +++*	P value
Total	1034	557	61
Colonoscopy results
Normal	612 (59.19)	342 (61.40)	34 (55.74)	0.556
NAPs	121 (11.70)	60 (10.77)	5 (8.20)	0.635
LRAs	209 (20.21)	107 (19.21)	14 (22.95)	0.749
AAs	79 (7.64)	39 (7.00)	6 (9.84)	0.702
CRC	13 (1.26)	9 (1.62)	2 (3.28)	0.406

Percentages were calculated within each Helicobacter pylori infection level. The histological grading criteria was shown in Figure 2. NAPs: Non-adenomatous polyps; LRAs: Low-risk adenomas; AAs: Advanced adenomas; CRC: Colorectal cancer; H. pylori: Helicobacter pylori.

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Citation: Shan N, Hou JJ, Jin CQ, Jin Q, Qin YH, Li WW. Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China. World J Gastrointest Surg 2026; 18(4): 117397
URL: https://www.wjgnet.com/1948-9366/full/v18/i4/117397.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i4.117397

Shan N, Hou JJ, Jin CQ, Jin Q, Qin YH, Li WW. Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China. World J Gastrointest Surg 2026; 18(4): 117397 [DOI: 10.4240/wjgs.v18.i4.117397]

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