Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China

doi:10.4240/wjgs.v18.i4.117397

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Apr 27, 2026; 18(4): 117397
Published online Apr 27, 2026. doi: 10.4240/wjgs.v18.i4.117397

Table 3 The association between Helicobacter pylori and the proportion of different types of colorectal polyps and colorectal cancer, n (%)

	H. pylori negative	H. pylori positive	P value
Total	4334	1652
Normal	2719 (62.73)	988 (59.81)	0.037
NAPs	503 (11.61)	186 (11.26)	0.707
LRAs	819 (18.90)	330 (19.98)	0.344
AAs	243 (5.61)	124 (7.51)	0.006
CRC	50 (1.15)	24 (1.45)	0.349

The showed a single variable association. NAPs: Non-adenomatous polyps; LRAs: Low-risk adenomas; AAs: Advanced adenomas; CRC: Colorectal cancer; H. pylori: Helicobacter pylori.

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Citation: Shan N, Hou JJ, Jin CQ, Jin Q, Qin YH, Li WW. Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China. World J Gastrointest Surg 2026; 18(4): 117397
URL: https://www.wjgnet.com/1948-9366/full/v18/i4/117397.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i4.117397

Shan N, Hou JJ, Jin CQ, Jin Q, Qin YH, Li WW. Helicobacter pylori positively associated with colorectal cancer and advanced, but not low-risk, adenomas: A retrospective study in China. World J Gastrointest Surg 2026; 18(4): 117397 [DOI: 10.4240/wjgs.v18.i4.117397]

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