Repairing the impaired gut vascular barrier as a novel therapeutic target for prolonged postoperative ileus: A scoping review

doi:10.4240/wjgs.v18.i4.117318

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Apr 27, 2026; 18(4): 117318
Published online Apr 27, 2026. doi: 10.4240/wjgs.v18.i4.117318

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Figure 5 Improving the function of intestinal microvascular endothelial cells and repairing the damaged gut vascular barrier as potential therapeutic targets for prolonged postoperative ileus. IL: Interleukin; eNOS: Endothelial nitric oxide synthase; MAPK: Mitogen-activated protein kinases; NF-kB: Nuclear factor kappa-B; AJ: Adherens junction; TJ: Tight junction; PPOI: Prolonged postoperative ileus; IMVEC: Intestinal microvascular endothelial cell. Created in BioRender (Supplementary material).

Citation: Shen DL, Wan L, Zhang XC, Fang YD, Jiang HC, Wei YC, Chen LF, Wu ZM, Ye CC, Pei C, Zhou H, Qian L. Repairing the impaired gut vascular barrier as a novel therapeutic target for prolonged postoperative ileus: A scoping review. World J Gastrointest Surg 2026; 18(4): 117318
URL: https://www.wjgnet.com/1948-9366/full/v18/i4/117318.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i4.117318

Shen DL, Wan L, Zhang XC, Fang YD, Jiang HC, Wei YC, Chen LF, Wu ZM, Ye CC, Pei C, Zhou H, Qian L. Repairing the impaired gut vascular barrier as a novel therapeutic target for prolonged postoperative ileus: A scoping review. World J Gastrointest Surg 2026; 18(4): 117318 [DOI: 10.4240/wjgs.v18.i4.117318]

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