Analysis of gut microbiota and serum I-FABP and PRDX1 levels in children with enterocolitis after congenital megacolon surgery

Table 2 Comparison of preoperative serum indexes between Hirschsprung-associated enterocolitis group and non-Hirschsprung-associated enterocolitis group

Items	Non HAEC group (n = 225)	HAEC group (n = 109)	t value	P value
CRP (mg/L)	3.58 ± 0.88	4.63 ± 1.29	-8.742	< 0.001
TNF-α (pg/mL)	32.76 ± 5.49	48.50 ± 5.76	-24.183	< 0.001
IL-6 (pg/mL)	26.00 ± 3.54	33.26 ± 5.24	-14.910	< 0.001
IL-8 (pg/mL)	16.33 ± 3.63	24.98 ± 5.04	-17.875	< 0.001
I-FABP (pg/mL)	84.35 ± 30.14	113.16 ± 35.10	-7.756	< 0.001
PRDX1 (μg/mL)	22.91 ± 6.40	32.05 ± 5.94	-12.523	< 0.001

PRDX1: Peroxiredoxin 1; I-FABP: Intestinal fatty acid-binding protein; CRP: C-reactive protein; TNF-α: Tumor necrosis factor-alpha; IL-6: Interleukin-6; IL-8: Interleukin-8.