Role of transversus abdominis plane block combined with multimodal analgesia in early recovery after radical colorectal cancer surgery

Table 5 Comparison of stress response indicators between two groups (mean ± SD)

Indicator	Time point	Observation group (n = 59)	Control group (n = 58)	t value	P value	After correction
IL-6 (pg/mL)	Preop day 1	12.8 ± 3.6	13.1 ± 3.8	0.447	0.656	NS
	Postop day 1	86.5 ± 18.4	112.3 ± 22.6	6.878	< 0.001	P < 0.001
	Postop day 3	45.2 ± 12.7	63.8 ± 15.3	7.256	< 0.001	P < 0.001
CRP (mg/L)	Preop day 1	5.2 ± 1.8	5.4 ± 1.9	0.588	0.558	NS
	Postop day 1	68.4 ± 15.2	89.6 ± 18.9	6.898	< 0.001	P < 0.001
	Postop day 3	38.7 ± 10.5	54.3 ± 13.8	6.95	< 0.001	P < 0.001
Cor (nmol/L)	Preop day 1	285.3 ± 45.6	289.7 ± 48.2	0.517	0.606	NS
	Postop day 1	486.8 ± 68.4	562.5 ± 82.3	5.538	< 0.001	P < 0.001
	Postop day 3	368.2 ± 52.7	428.6 ± 64.5	5.685	< 0.001	P < 0.001

Bonferroni method was used for multiple comparison correction of 3 time points for each indicator, with corrected significance level α = 0.017. NS indicates not statistically significant (P > 0.05). P < 0.001 after correction indicates remaining statistically significant after correction. IL-6: Interleukin-6; CRP: C-reactive protein; Cor: Cortisol.