Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study

doi:10.4240/wjgs.v18.i3.115972

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World Journal of Gastrointestinal Surgery

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1948-9366

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Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115972
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115972

Table 5 Outcomes stratified by etiology, n (%) or mean ± SD

Etiology and outcome	EEN group	DEN group	P value
Biliary pancreatitis	n = 24	n = 21
Mortality	1 (4.2)^a	4 (19.0)^b	0.041
Infectious complications	4 (16.7)^a	8 (38.1)^b	0.039
Hospital stay (days)	17.2 ± 5.8^a	24.6 ± 7.9^b	0.002
Organ failure	5 (20.8)^a	10 (47.6)^b	0.038
Alcoholic pancreatitis	n = 17	n = 17
Mortality	1 (5.9)^a	3 (17.6)^b	0.042
Infectious complications	2 (11.8)^a	6 (35.3)^b	0.016
Hospital stay (days)	19.8 ± 6.4^a	27.2 ± 8.8^b	0.006
Organ failure	4 (23.5)	7 (41.2)	0.274
Hypertriglyceridemia	n = 6	n = 5
Mortality	0 (0.0)	1 (20.0)	0.455
Infectious complications	1 (16.7)	2 (40.0)	0.524
Hospital stay (days)	20.5 ± 7.2	28.8 ± 9.6	0.178
Organ failure	2 (33.3)	3 (60.0)	0.524
Idiopathic pancreatitis	n = 5	n = 5
Mortality	1 (20.0)	1 (20.0)	1.000
Infectious complications	2 (40.0)	2 (40.0)	1.000
Hospital stay (days)	18.6 ± 6.8	26.4 ± 10.2	0.246
Organ failure	1 (20.0)	2 (40.0)	0.524

^aP < 0.05 vs the delayed enteral nutrition group.

^bP < 0.05 vs the early enteral nutrition group.

EEN: Early enteral nutrition; DEN: Delayed enteral nutrition.

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Citation: Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115972.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115972

Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972 [DOI: 10.4240/wjgs.v18.i3.115972]

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