Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study

doi:10.4240/wjgs.v18.i3.115972

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115972
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115972

Table 3 Secondary outcomes and nutritional parameters, n (%) or mean ± SD

Outcome	EEN group (n = 52)	DEN group (n = 48)	P value
Feeding intolerance	7 (13.5)	8 (16.7)	0.645
Time to full nutrition (days)	4.2 ± 1.6^a	8.5 ± 2.8^b	< 0.001
Local complications
Pancreatic necrosis	16 (30.8)	18 (37.5)	0.473
Peripancreatic fluid collections	22 (42.3)	24 (50.0)	0.435
Pancreatic pseudocyst	5 (9.6)	7 (14.6)	0.434
Interventional procedures	8 (15.4)^a	16 (33.3)^b	0.031
Albumin (g/L)
Baseline	36.4 ± 5.2	35.8 ± 5.6	0.579
Day 7	34.8 ± 4.6^a	31.2 ± 5.8^b	0.001
Day 14	33.2 ± 4.8^a	28.6 ± 5.4^b	< 0.001
Prealbumin (mg/L)
Baseline	186 ± 42	182 ± 46	0.646
Day 7	168 ± 38^a	142 ± 44^b	0.002
Day 14	172 ± 36^a	136 ± 48^b	< 0.001
C-reactive protein day 7 (mg/L)	82 ± 34^a	126 ± 52^b	< 0.001
Procalcitonin day 7 (ng/mL)	1.8 ± 0.9^a	3.6 ± 1.8^b	< 0.001

^aP < 0.05 vs the delayed enteral nutrition group.

^bP < 0.05 vs the early enteral nutrition group.

EEN: Early enteral nutrition; DEN: Delayed enteral nutrition.

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Citation: Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115972.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115972

Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972 [DOI: 10.4240/wjgs.v18.i3.115972]

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