Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study

doi:10.4240/wjgs.v18.i3.115972

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115972
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115972

Table 2 Primary clinical outcomes between early enteral nutrition and delayed enteral nutrition groups, n (%) or mean ± SD

Outcome	EEN group (n = 52)	DEN group (n = 48)	P value
Mortality	3 (5.8)^a	9 (18.8)^b	0.038
Infectious complications	9 (17.3)^a	18 (37.5)^b	0.019
Infected pancreatic necrosis	4 (7.7)^a	11 (22.9)^b	0.028
Bacteremia	2 (3.8)	4 (8.3)	0.335
Pneumonia	2 (3.8)	5 (10.4)	0.191
Urinary tract infection	1 (1.9)	2 (4.2)	0.515
Length of hospital stay (days)	18.6 ± 6.2^a	26.4 ± 8.5^b	< 0.001
Persistent organ failure	12 (23.1)^a	22 (45.8)^b	0.014
Respiratory failure	6 (11.5)^a	14 (29.2)^b	0.022
Cardiovascular failure	5 (9.6)^a	12 (25.0)^b	0.036
Renal failure	4 (7.7)	8 (16.7)	0.162
ICU admission	18 (34.6)	24 (50.0)	0.113
ICU length of stay (days)	6.8 ± 3.4^a	10.2 ± 5.1^b	0.006

^aP < 0.05 vs the delayed enteral nutrition group.

^bP < 0.05 vs the early enteral nutrition group.

EEN: Early enteral nutrition; DEN: Delayed enteral nutrition; ICU: Intensive care unit.

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Citation: Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115972.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115972

Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972 [DOI: 10.4240/wjgs.v18.i3.115972]

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