Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study

doi:10.4240/wjgs.v18.i3.115972

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115972
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115972

Table 1 Baseline demographic and clinical characteristics, n (%)

Variable	EEN group (n = 52)	DEN group (n = 48)	P value
Age (years), mean ± SD	48.3 ± 14.2	50.1 ± 13.8	0.512
Male gender	34 (65.4)	30 (62.5)	0.756
BMI (kg/m²), mean ± SD	24.8 ± 3.6	25.3 ± 3.9	0.493
Etiology			0.897
Biliary	24 (46.2)	21 (43.8)
Alcoholic	17 (32.7)	17 (35.4)
Hypertriglyceridemia	6 (11.5)	5 (10.4)
Idiopathic	5 (9.6)	5 (10.4)
Comorbidities
Diabetes mellitus	12 (23.1)	10 (20.8)	0.776
Hypertension	18 (34.6)	16 (33.3)	0.889
Hyperlipidemia	9 (17.3)	8 (16.7)	0.930
APACHE II score, mean ± SD	12.4 ± 3.8	12.8 ± 4.1	0.603
Balthazar CT severity index, mean ± SD	6.2 ± 1.8	6.5 ± 1.9	0.415
WBC count (× 10⁹/L), mean ± SD	14.2 ± 4.3	14.8 ± 4.6	0.499
Serum amylase (U/L), mean ± SD	862 ± 346	894 ± 372	0.651
C-reactive protein (mg/L), mean ± SD	186 ± 72	192 ± 78	0.684

BMI: Body mass index; APACHE: Acute Physiology and Chronic Health Evaluation; CT: Computed tomography; WBC: White blood cells; DEN: Delayed enteral nutrition; EEN: Early enteral nutrition.

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Citation: Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115972.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115972

Jiang ML, Bao JP, Jiang SC, Xu FG. Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; 18(3): 115972 [DOI: 10.4240/wjgs.v18.i3.115972]

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