Retrospective analysis cognitive function changes in elderly depressive patients after gastrointestinal tumor surgery and exploration of cholinergic mechanism

doi:10.4240/wjgs.v18.i3.115910

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 3

This Article

(26)

(31)

(0)

(407)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115910
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115910

Table 4 Mediation effect analysis of the inflammatory mediation model and the cholinergic mediation model

Model	Pathway	Effect estimates	Boot SE	Boot 95%LLCI	Boot 95%ULCI	Percentage mediated (%)
Inflammatory mediator	HAMD to IL-6 to MoCA	-0.098	0.040	-0.188	-0.032	19.7
Cholinergic mediator	HAMD to CHE to MoCA	-0.085	0.036	-0.169	-0.025	17.2

95%LLCI: 95% low limit confidence interval; 95%ULCI: 95% upper limit confidence interval; HAMD: Hamilton Depression Rating Scale; IL-6: Interleukin-6; MoCA: Montreal Cognitive Assessment; CHE: Cholinesterase.

Full Size Table

Citation: Li W, Ye ZY, Zhao JQ. Retrospective analysis cognitive function changes in elderly depressive patients after gastrointestinal tumor surgery and exploration of cholinergic mechanism. World J Gastrointest Surg 2026; 18(3): 115910
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115910.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115910

Li W, Ye ZY, Zhao JQ. Retrospective analysis cognitive function changes in elderly depressive patients after gastrointestinal tumor surgery and exploration of cholinergic mechanism. World J Gastrointest Surg 2026; 18(3): 115910 [DOI: 10.4240/wjgs.v18.i3.115910]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.