Prognostic value of a nomogram model for pancreatic cancer incorporating the systemic immune-inflammation and prognostic nutritional indices

doi:10.4240/wjgs.v18.i3.115906

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 3

This Article

(33)

(27)

(0)

(15)

(554)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115906
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115906

Table 2 Univariable and multivariable Cox regression analyses for the prognosis of pancreatic ductal adenocarcinoma patients

Clinicopathologic factors	Univariable analysis		P value	Multivariable analysis		P value
Clinicopathologic factors	HR	95%CI	P value	HR	95%CI	P value
Gender
Female	1 (reference)		-	-	-	-
Male	0.955	0.634-1.438	0.824	-	-	-
Age (years)
≤ 65	1 (reference)		-	-	-	-
> 65	1.107	0.736-1.665	0.626	-	-	-
Underlying diseases
No	1 (reference)		-	-	-	-
Yes	0.992	0.661-1.491	0.970	-	-	-
Surgical methods
Endoscopic surgery	1 (reference)		-	-	-	-
Open surgery	1.101	0.570-2.128	0.774	-	-	-
Tumor location
Pancreatic body/tail	1 (reference)		-	-	-	-
Pancreatic head	0.754	0.495-1.147	0.187	-	-	-
Tumor maximum diameter (cm)
≤ 3	1 (reference)		-	-	-	-
> 3	1.816	1.194-2.762	0.005^a	1.592	0.962-2.633	0.070
T staging
T1-T2	1 (reference)	-	-	-	-	-
T3-T4	1.568	1.013-2.427	0.043^a	1.061	0.624-1.802	0.827
N grouping
N0	1 (reference)	-	-	-	-	-
N1-N2	1.325	0.877-2.002	0.181	-		-
TNM staging
I-II	1 (reference)	-	-	-	-	-
III	1.129	0.601-2.120	0.707	-	-	-
Degree of tumor differentiation
Moderately or well-differentiated	1 (reference)	-	-	-	-	-
Poorly differentiated	1.607	1.057-2.442	0.026^a	1.614	1.036-2.515	0.034^a
Surgical margins
Negative	1 (reference)	-	-	-	-	-
Positive	1.033	0.451-2.371	0.938	-	-	-
Vascular tumor thrombus
No	1 (reference)	-	-	-	-	-
Yes	1.058	0.700-1.599	0.790	-	-	-
Vascular/nerve invasion
No	1 (reference)	-	-	-	-	-
Yes	1.715	0.859-3.426	0.126	-	-	-
Lymph node metastasis
No	1 (reference)	-	-	-	-	-
Yes	1.251	0.825-1.897	0.292	-	-	-
Postoperative adjuvant chemotherapy
No	1 (reference)	-	-	-	-	-
Yes	0.575	0.373-0.885	0.012^a	0.561	0.360-0.874	0.011^a
Recent postoperative complications
No	1 (reference)	-	-	-	-	-
Yes	1.218	0.763-1.945	0.408	-	-	-
CEA (ng/mL)
≤ 5	1 (reference)	-	-	-	-	-
> 5	0.917	0.562-1.495	0.728	-	-	-
CA19-9 (U/mL)
≤ 37	1 (reference)	-	-	-	-	-
> 37	2.021	1.142-3.576	0.016^a	1.844	1.021-3.330	0.043^a
SII
≤ 335.82	1 (reference)	-	-	-	-	-
> 335.82	1.844	1.194-2.849	0.006^a	1.891	1.217-2.938	0.005^a
PNI
≤ 44.45	1 (reference)	-	-	-	-	-
> 44.45	1.990	1.305-3.034	0.001^a	2.149	1.381-3.343	0.001^a

^aP < 0.05.

HR: Hazard ratio; CI: Confidence interval; TNM: Tumor-node-metastasis; SII: Systemic immune inflammation index; PNI: Prognostic nutritional index; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9.

Full Size Table

Citation: Tang J, Ding SL, Wu Y, Wu YP, Yuan XB, Wu PF, Sha DS. Prognostic value of a nomogram model for pancreatic cancer incorporating the systemic immune-inflammation and prognostic nutritional indices. World J Gastrointest Surg 2026; 18(3): 115906
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115906.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115906

Tang J, Ding SL, Wu Y, Wu YP, Yuan XB, Wu PF, Sha DS. Prognostic value of a nomogram model for pancreatic cancer incorporating the systemic immune-inflammation and prognostic nutritional indices. World J Gastrointest Surg 2026; 18(3): 115906 [DOI: 10.4240/wjgs.v18.i3.115906]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.