Correlation between the initiation of early enteral nutrition and anastomotic fistula after pancreaticoduodenectomy

doi:10.4240/wjgs.v18.i3.115621

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 115621
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115621

Table 4 Comparison of anastomotic leakage between the 2 groups, n (%)

Type of AL	Study (n = 100)	Control (n = 100)	χ²	P value	OR (95%CI)
Overall AL	18 (18.00)	32 (32.00)	5.227	0.022	0.467 (0.241-0.904)
Pancreatic fistula (grade B/C)	12 (12.00)	25 (25.00)	5.604	0.018	0.409 (0.192-0.870)
Bile leak	6 (6.00)	9 (9.00)	0.617	0.432	0.652 (0.223-1.907)
Gastroenteric AL	3 (3.00)	6 (6.00)	-	0.498^a	0.500 (0.129-1.950)
≥ 2 concurrent fistulas	2 (2.00)	5 (5.00)	-	0.445^a	0.400 (0.079-2.014)

^aP < 0.05, the study group vs the control group.

AL: Anastomotic leakage; OR: Odds ratio; CI: Confidence interval.

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Citation: Yan B, Zhang LQ, Shen YQ. Correlation between the initiation of early enteral nutrition and anastomotic fistula after pancreaticoduodenectomy. World J Gastrointest Surg 2026; 18(3): 115621
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/115621.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.115621

Yan B, Zhang LQ, Shen YQ. Correlation between the initiation of early enteral nutrition and anastomotic fistula after pancreaticoduodenectomy. World J Gastrointest Surg 2026; 18(3): 115621 [DOI: 10.4240/wjgs.v18.i3.115621]

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