Dachengqitang mitigates endoscopic retrograde cholangiopancreatography-induced pancreatitis

doi:10.4240/wjgs.v18.i3.112405

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Mar 27, 2026; 18(3): 112405
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.112405

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Figure 5 In vivo experiments have demonstrated that clearance of macrophages can improve intestinal function and the integrity of the epithelium. A: Histological examination staining showing intestinal morphology in Control group; B: In Control group, immunofluorescence staining displaying ZO-1 expression in intestinal tissues; C: In Control group, immunofluorescence staining showing CD86 expression; D: Histological examination staining showing intestinal morphology in SAP group; E: In SAP group, immunofluorescence staining displaying ZO-1 expression in intestinal tissues; F: In SAP group, immunofluorescence staining showing CD86 expression; G: Histological examination staining showing intestinal morphology in SAP model treated with DCQT (SAP + DCQT) group; H: In SAP + DCQT group, immunofluorescence staining displaying ZO-1 expression in intestinal tissues; I: In SAP + DCQT group, immunofluorescence staining showing CD86 expression; J: Histological examination staining showing intestinal morphology in SAP + DCQT + CI group; K: In SAP + DCQT + CI group, immunofluorescence staining displaying ZO-1 expression in intestinal tissues; L: In SAP + DCQT + CI group, immunofluorescence staining showing CD86 expression; M: Quantitative analysis of ZO-1 fluorescence intensity; N: Quantitative analysis of CD86 fluorescence intensity. SAP significantly decreased ZO-1 expression and increased CD86 expression, while DCQT treatment restored ZO-1 levels and reduced CD86 expression. ^aP < 0.05. DCQT: Dachengqitang.

Citation: Zheng L, Wang J, Xu MQ, Jiang W, Qian L, Ge Y, Feng MK, Zhu YM, Wang MJ, Sun SS, Liu CK, Wang XM, Zhang C. Dachengqitang mitigates endoscopic retrograde cholangiopancreatography-induced pancreatitis. World J Gastrointest Surg 2026; 18(3): 112405
URL: https://www.wjgnet.com/1948-9366/full/v18/i3/112405.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i3.112405

Zheng L, Wang J, Xu MQ, Jiang W, Qian L, Ge Y, Feng MK, Zhu YM, Wang MJ, Sun SS, Liu CK, Wang XM, Zhang C. Dachengqitang mitigates endoscopic retrograde cholangiopancreatography-induced pancreatitis. World J Gastrointest Surg 2026; 18(3): 112405 [DOI: 10.4240/wjgs.v18.i3.112405]

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