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Retrospective Cohort Study
©Author(s) (or their employer(s)) 2026.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 115427
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.115427
Figure 3
Figure 3 Dual-cut-off funnel validation. A: Confusion matrix (high-sensitivity cut-off of 0.020). Confusion matrix for the entire cohort (n = 134) at the screening threshold of 0.020. The model correctly identified 20 of 21 deaths (sensitivity = 95.2%) with only one false-negative case, achieving a negative predictive value of 95.8% and supporting its use as a high-sensitivity screening criterion; B: Funnel pathway diagram. Flow chart of the dual-cut-off funnel strategy. Step 1 (≥ 0.020) flagged 92 high-risk patients (68.7%). Step 2 (≥ 0.121) confirmed 17 for intensive intervention while downgrading 75 to standard care, reducing advanced resource use by 53% in this cohort.


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