Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy

doi:10.4240/wjgs.v18.i2.114743

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World Journal of Gastrointestinal Surgery

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1948-9366

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World J Gastrointest Surg. Feb 27, 2026; 18(2): 114743
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114743

Table 5 Multivariable logistic regression analysis of independent variables for prediction of failure to complete adjuvant chemotherapy due to mortality toxicity, disease progression, or non-chemotherapy-related complications

Variable	Mortality		Toxicity		Disease progression		NCRC
Variable	Standardized coefficient	P value	Standardized coefficient	P value	Standardized coefficient	P value	Standardized coefficient	P value
PMI	0.0002	0.0651	-0.0001	0.7255	-0.0004	0.7784	0.0002	0.1798
HUAC	-0.0013	0.4073	-0.0059	0.0431	0.0025	0.8818	0.0003	0.8697
Sarcopenia	0.0173	0.7343	-0.0284	0.7622	-0.1182	0.1523	-0.0213	0.7528
Age	0.0006	0.7556	0.0028	0.4599	-0.1658	0.4587	0.0006	0.8234
Octogenarian	-0.0085	0.9228	0.0238	0.8839	-0.0107	0.2495	-0.0770	0.5109
ASA	-0.0165	0.5436	-0.0316	0.5292	-0.1152	0.8092	0.0471	0.1925
CR-POPF	0.0279	0.6328	-0.0923	0.3929	-0.1012	0.2268	0.0568	0.4641
C-D > III	0.0974	0.1593	0.1013	0.4269	0.0051	0.3683	-0.1046	0.2545
LOS	-0.0025	0.3498	0.0043	0.3783	0.0931	0.2442	-0.0035	0.3274
Cardiac disease	0.0469	0.3976	-0.0308	0.7635	-0.0004	0.3024	-0.0833	0.2578
COPD	-0.0491	0.5281	-0.1133	0.4311	0.0025	0.7784	-0.0484	0.6396

NCRC: Non-chemotherapy-related complications; PMI: Psoas muscle index; HUAC: Hounsfield unit average calculation; ASA: American Society of Anesthesiologists; CR-POPF: Clinically relevant-postoperative pancreatic fistula; C-D: Clavien-Dindo; LOS: Length of stay; COPD: Chronic obstructive pulmonary disease.

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Citation: Hajibandeh S, Hajibandeh S, Mckittrick H, Imrani U, Varghese A, Balasubramaniam R, Durkin D, Athwal TS. Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy. World J Gastrointest Surg 2026; 18(2): 114743
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/114743.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.114743

Hajibandeh S, Hajibandeh S, Mckittrick H, Imrani U, Varghese A, Balasubramaniam R, Durkin D, Athwal TS. Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy. World J Gastrointest Surg 2026; 18(2): 114743 [PMID: 41809357 DOI: 10.4240/wjgs.v18.i2.114743]

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