Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy

doi:10.4240/wjgs.v18.i2.114743

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 114743
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114743

Table 3 Multivariable logistic regression analysis of independent variables for prediction of time to adjuvant chemotherapy, completion of adjuvant chemotherapy, 1-year, 3-years and overall survival

Variable	Time to AC		Completion of AC		1-year survival		3-years survival		Overall survival
Variable	Standardized coefficient	P value	Standardized coefficient	P value	Standardized coefficient	P value	Standardized coefficient	P value	Standardized coefficient	P value
PMI	-0.0109	0.2405	-0.0003	0.1985	0.0001	0.3790	0.0001	0.9774	0.3140	0.3065
HUAC	0.5074	0.0005	0.0124	0.0486	0.0005	0.8616	0.0020	0.5941	0.4704	0.9206
Sarcopenia	6.3857	0.1676	0.2114	0.1188	-0.0059	0.9531	0.0551	0.6641	-33.5165	0.8262
Age	0.1439	0.4434	-0.0036	0.5082	-0.0074	0.0689	0.0010	0.8328	-1.6205	0.7927
Octogenarian	2.9289	0.7158	0.2488	0.2923	0.2749	0.1151	0.5160	0.0201	538.2032	0.0433
ASA	1.7999	0.4676	0.0005	0.9941	0.0031	0.9535	0.0326	0.6292	45.9027	0.5729
CR-POPF	7.2686	0.1739	0.1050	0.5017	0.0878	0.4456	0.0525	0.7182	228.5744	0.1931
C-D > III	5.9580	0.3445	0.0764	0.6788	-0.0841	0.5361	-0.0448	0.7943	-106.1970	0.6078
LOS	0.6556	0.0076	-0.0033	0.6392	-0.0010	0.8462	-0.0101	0.1290	-7.6509	0.3385
Cardiac disease	2.8105	0.5780	-0.1286	0.3855	-0.0572	0.5997	-0.2473	0.0747	-291.7777	0.0804
COPD	-9.9204	0.1640	0.4382	0.0368	0.1614	0.2935	0.1030	0.5954	111.0465	0.6344

AC: Adjuvant chemotherapy; PMI: Psoas muscle index; HUAC: Hounsfield unit average calculation; ASA: American Society of Anesthesiologists; CR-POPF: Clinically relevant-postoperative pancreatic fistula; C-D: Clavien-Dindo; LOS: Length of stay; COPD: Chronic obstructive pulmonary disease.

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Citation: Hajibandeh S, Hajibandeh S, Mckittrick H, Imrani U, Varghese A, Balasubramaniam R, Durkin D, Athwal TS. Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy. World J Gastrointest Surg 2026; 18(2): 114743
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/114743.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.114743

Hajibandeh S, Hajibandeh S, Mckittrick H, Imrani U, Varghese A, Balasubramaniam R, Durkin D, Athwal TS. Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy. World J Gastrointest Surg 2026; 18(2): 114743 [PMID: 41809357 DOI: 10.4240/wjgs.v18.i2.114743]

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