Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery

doi:10.4240/wjgs.v18.i2.114607

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 114607
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114607

Table 8 Cox regression analysis of overall survival factors

Factor	Univariate analysis		Multivariate analysis
Factor	HR (95%CI)	P value	HR (95%CI)	P value
Age ≥ 65 years	2.341 (0.756-7.254)	0.140
NRS2002 ≥ 3 points	4.267 (1.274-14.289)	0.018	3.524 (1.089-11.404)	0.036
PNI < 45	3.156 (1.024-9.724)	0.045
GPS ≥ 1 point	2.789 (0.821-9.480)	0.100
TNM stage III	5.234 (1.578-17.357)	0.007	4.267 (1.241-14.658)	0.021
Neural invasion	2.456 (0.798-7.564)	0.118
RDI < 85%	2.987 (0.975-9.156)	0.055

BMI: Body mass index; NRS2002: Nutritional Risk Screening 2002; CONUT: Controlling Nutritional Status; PNI: Prognostic Nutritional Index; GPS: Glasgow Prognostic Score; RDI: Relative dose intensity; CI: Confidence interval; HR: Hazard ratio.

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Citation: Zhou K, Tu RF, Lu LH, Zhang H. Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery. World J Gastrointest Surg 2026; 18(2): 114607
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/114607.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.114607

Zhou K, Tu RF, Lu LH, Zhang H. Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery. World J Gastrointest Surg 2026; 18(2): 114607 [PMID: 41809355 DOI: 10.4240/wjgs.v18.i2.114607]

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