Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery

doi:10.4240/wjgs.v18.i2.114607

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 114607
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114607

Table 7 Cox regression analysis of disease-free survival factors

Factor	Univariate analysis		Multivariate analysis
Factor	HR (95%CI)	P value	HR (95%CI)	P value
NRS2002 ≥ 3 points	3.241 (1.315-7.985)	0.011	2.847 (1.124-7.214)	0.027
CONUT ≥ 5 points	2.687 (1.142-6.319)	0.024
PNI < 45	2.834 (1.189-6.754)	0.019
GPS ≥ 1 point	2.156 (0.886-5.245)	0.090
TNM stage III	4.125 (1.754-9.702)	0.001	3.162 (1.287-7.768)	0.012
Vascular invasion	2.341 (0.987-5.551)	0.053
RDI < 85%	3.156 (1.387-7.182)	0.006	2.536 (1.089-5.903)	0.031

NRS2002: Nutritional Risk Screening 2002; CONUT: Controlling Nutritional Status; PNI: Prognostic Nutritional Index; GPS: Glasgow Prognostic Score; RDI: Relative dose intensity; CI: Confidence interval; HR: Hazard ratio.

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Citation: Zhou K, Tu RF, Lu LH, Zhang H. Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery. World J Gastrointest Surg 2026; 18(2): 114607
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/114607.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.114607

Zhou K, Tu RF, Lu LH, Zhang H. Impact of nutritional status on treatment completion and prognosis during adjuvant chemotherapy following gastric cancer surgery. World J Gastrointest Surg 2026; 18(2): 114607 [PMID: 41809355 DOI: 10.4240/wjgs.v18.i2.114607]

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