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Retrospective Study
©Author(s) (or their employer(s)) 2026.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 114607
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114607
Table 5 Incidence of chemotherapy adverse reactions between groups, n (%)
Adverse reactionNutritional risk group (n = 37)
Non-nutritional risk group (n = 43)
P value
Any grade
≥ grade 3
Any grade
≥ grade 3
Hematologic toxicity
Leukopenia32 (86.5)16 (43.2)31 (72.1)8 (18.6)0.015
Neutropenia30 (81.1)15 (40.5)29 (67.4)7 (16.3)0.012
Thrombocytopenia24 (64.9)8 (21.6)22 (51.2)4 (9.3)0.127
Anemia28 (75.7)6 (16.2)26 (60.5)3 (7.0)0.201
Non-hematologic toxicity
Nausea and vomiting34 (91.9)12 (32.4)36 (83.7)6 (14.0)0.042
Diarrhea22 (59.5)10 (27.0)19 (44.2)4 (9.3)0.039
Mucositis18 (48.6)5 (13.5)15 (34.9)2 (4.7)0.159
Hand-foot syndrome25 (67.6)7 (18.9)24 (55.8)4 (9.3)0.221
Peripheral neuropathy21 (56.8)4 (10.8)19 (44.2)2 (4.7)0.298
Hepatic dysfunction16 (43.2)3 (8.1)13 (30.2)1 (2.3)0.242
Renal dysfunction12 (32.4)2 (5.4)8 (18.6)1 (2.3)0.398


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