Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters

doi:10.4240/wjgs.v18.i2.114286

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 114286
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114286

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Figure 5 Sensitivity of patient-derived tumor-like cell clusters to FOLFOX, FOLFIRI and FOLFOXIRI. A: Microscopic images of drug killing effects on patient-derived tumor-like cell clusters (PTCs); B: Inhibitory effects of FOLFOX, FOLFIRI and FOLFOXIRI on 54 PTCs. From top to bottom, the samples are represented sequentially from colorectal cancer (CRC)-1 to CRC-54. 0 represented P_A = 0 (blue), 1.0 represented P_A = 1.0 (red); C: The cases of strong killing, effective killing and ineffective killing on PTC models; D: The percentage of strong killing, effective killing and ineffective killing on PTC models. CRC: Colorectal cancer; PTC: Patient-derived tumor-like cell cluster.

Citation: Lin FL, Zhou LM, Ye YJ, Luo XL, Ji XL, Chen SQ, Xie JG, Jin BF, Liu ZD. Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters. World J Gastrointest Surg 2026; 18(2): 114286
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/114286.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.114286

Lin FL, Zhou LM, Ye YJ, Luo XL, Ji XL, Chen SQ, Xie JG, Jin BF, Liu ZD. Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters. World J Gastrointest Surg 2026; 18(2): 114286 [PMID: 41809350 DOI: 10.4240/wjgs.v18.i2.114286]

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