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Editorial
©Author(s) (or their employer(s)) 2026.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 113867
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113867
Figure 2
Figure 2 Histologic comparison of colorectal carcinoma subtypes. A: High-power view of a conventional adenocarcinoma, not otherwise specified, which is the commonest subtype of colorectal cancer. There is architectural disorganization with partial glandular fusion, consistent with a moderately differentiated (grade 2) adenocarcinoma; B: High-power view of a medullary carcinoma of the colon. Unlike conventional adenocarcinoma, this subtype exhibits diffuse proliferation of epithelial cells without glandular formation and is therefore commonly described as an undifferentiated carcinoma. Paradoxically, it generally has a better prognosis compared to conventional adenocarcinoma.


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