Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 113525
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113525

Table 6 Comparison of cognitive function scores between two groups (points), mean ± SD

Parameter	DEX conventional anesthesia group (n = 95)	DEX preconditioning anesthesia group (n = 87)	t value	P value
Preoperative	27.35 ± 1.24	27.42 ± 1.18	0.398	0.691
Postoperative 6 hours	24.72 ± 2.15	25.53 ± 1.87	2.683	0.008
Postoperative 12 hours	25.63 ± 1.96	26.24 ± 1.65	2.254	0.025
Postoperative 24 hours	26.85 ± 1.47	26.92 ± 1.32	0.296	0.767
Postoperative 48 hours	26.93 ± 1.25	27.15 ± 1.18	1.236	0.218

DEX: Dexmedetomidine.

Citation: Chen M, Chen FC, Pan Q, Liu ZH. Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(2): 113525
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/113525.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.113525

Chen M, Chen FC, Pan Q, Liu ZH. Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(2): 113525 [PMID: 41809358 DOI: 10.4240/wjgs.v18.i2.113525]

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