Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 113525
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113525

Table 3 Comparison of postoperative sedation scores (points) between two groups, mean ± SD

Parameter	DEX conventional anesthesia group (n = 95)	DEX preconditioning anesthesia group (n = 87)	t value	P value
Postoperative 6 hours	4.23 ± 0.47	4.26 ± 0.35	0.440	0.660
Postoperative 12 hours	3.97 ± 0.39	4.01 ± 0.32	0.847	0.398
Postoperative 24 hours	3.52 ± 0.45	3.66 ± 0.68	1.652	0.101
Postoperative 48 hours	3.07 ± 0.26	3.14 ± 0.33	1.470	0.143

DEX: Dexmedetomidine.

Citation: Chen M, Chen FC, Pan Q, Liu ZH. Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(2): 113525
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/113525.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.113525

Chen M, Chen FC, Pan Q, Liu ZH. Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(2): 113525 [PMID: 41809358 DOI: 10.4240/wjgs.v18.i2.113525]

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