Prediction of lymphovascular invasion in rectal cancer based on multimodal magnetic resonance imaging radiomics model

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World Journal of Gastrointestinal Surgery

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1948-9366

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World J Gastrointest Surg. Feb 27, 2026; 18(2): 113021
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113021

Table 3 Logistic regression analysis of lymphovascular invasion predictors

Variable	Univariate analysis		Multivariate analysis
Variable	OR (95%CI)	P value	OR (95%CI)	P value
Gender (male vs female)	1.590 (1.037-2.438)	0.032	1.421 (0.859-2.351)	0.168
Tumor diameter (≥ 4 cm vs < 4 cm)	2.834 (1.781-4.504)	< 0.001	2.142 (1.251-3.668)	0.006
CEA (≥ 5 ng/mL vs < 5 ng/mL)	2.953 (1.712-5.088)	< 0.001	2.261 (1.224-4.191)	0.009
CA19-9 (≥ 37 U/mL vs < 37 U/mL)	1.892 (1.181-3.031)	0.008	1.354 (0.782-2.334)	0.284
Differentiation (poor vs well/moderate)	4.571 (2.451-8.529)	< 0.001	3.824 (1.912-7.654)	< 0.001
T stage (T3-4 vs T1-2)	3.421 (1.889-6.194)	< 0.001	2.581 (1.329-5.003)	0.005
N stage (N1-2 vs N0)	2.903 (1.831-4.604)	< 0.001	2.314 (1.381-3.872)	0.001
Perineural invasion (positive vs negative)	3.984 (2.318-6.837)	< 0.001	2.951 (1.612-5.406)	< 0.001

CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; OR: Odds ratio; CI: Confidence interval.

Citation: Zhu ZH, Liang Y, Shi M. Prediction of lymphovascular invasion in rectal cancer based on multimodal magnetic resonance imaging radiomics model. World J Gastrointest Surg 2026; 18(2): 113021
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/113021.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.113021

Zhu ZH, Liang Y, Shi M. Prediction of lymphovascular invasion in rectal cancer based on multimodal magnetic resonance imaging radiomics model. World J Gastrointest Surg 2026; 18(2): 113021 [PMID: 41809348 DOI: 10.4240/wjgs.v18.i2.113021]

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